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Production

In the process of using media there are a lot of advantages by using serum-replacements as the actual content of FBS is not known. 

Some advantages of using synthetic alternatives include: 

  • - Improved reproducibility of results from different laboratories and over time since variation due to batch change of serum is avoided. 
  • - Easier downstream processing of products from cultured cells. 
  • - Side effects of serum are avoided. 
  • - Bioassays are free from interferences buy serum proteins. 
  • - There is no danger of degradation of sensitive proteins by serum proteases. 
  • - They permit selective culture of differentiated and producing cell types from the heterogenous cultures.