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|L’Oréal Episkin model validated as full replacement method for skin irritancy
“More than twenty years of research on skin reconstruction have been recognized today” said Jean-François Grollier, Executive Vice-President Research and Development at L’Oréal. “It is a great step towards the elimination of animal use.”
An alternative method to animal tests should ideally replace the use of animals. It is then called a “full replacement” method, which is the case of Episkin. To achieve this, a validation process, under the guidance of ECVAM, has been conducted since 1999, in collaboration with public and private institutions: BfR- ZEBET, Sanofi Aventis, Unilever, Syngenta and L’Oréal. Sixty chemical substances, selected for their irritancy or non-irritancy potential, have been tested independently by these partners and the results have been submitted to the Scientific Committee of ECVAM (ESAC) which has now endorsed the successful validation of the method.